Sohila zadran 2

sohila zadran One of the most impressive individuals that have graduated at light speed over the last decade from University of Southern California would have to be Dr. Sohila Zadran who has written some of the most amazing resource information on the website: Proceedings of the National Academy of Sciences of the United States of America. sohila zadran Below is a brief overview of the research conducted by Sohila Zadran,, Qingyu Qin, Xiaoning Bi, Homera Zadran, Young Kima, Michael R. Foy, Richard Thompson and Michel Baudry. sohila zadran 17- -Estradiol (E2) is a steroid hormone involved in numerous brain functions. E2 regulates synaptic plasticity in part by enhancing NMDA receptor function and spine density in the hippocampus, resulting in increased long-term potentiation and facilitation of learning and memory. As the calcium-dependent neutral protease, calpain, is also involved in these processes, we tested whether E2 could activate calpain and examined the functional consequences of E2-mediated calpain activation in hippocampus. Calpain activity was analyzed by a &amp;#64258;uorescence resonance energy transfer (FRET)-based assay that allows both quantitative determination and spatial resolution. E2 rapidly activated calpain in cultured cortical and hippocampal neurons, prominently in dendrites and dendritic spines.